WHAT SIZE RNA LOOP HOLDS BULK SOLVENT

被引：10

作者：

FERNANDEZ, A

GUSTAVO, AB

CENDRA, H

机构：

[1] UNIV NACL SUR,CONSEJO NACL INVEST CIENT & TECN,INIBIBB,INST INVEST BIOQUIM,RA-8000 BAHIA BLANCA,ARGENTINA

[2] UNIV NACL SUR,CONSEJO NACL INVEST CIENT & TECN,INIBIBB,INST MATEMAT,RA-8000 BAHIA BLANCA,ARGENTINA

来源：

CHEMICAL PHYSICS LETTERS | 1995年 / 242卷 / 4-5期

关键词：

D O I：

10.1016/0009-2614(95)00776-Z

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The loss in conformational entropy that results from the closure of a loop in a polymer chain has been derived in cases where the effects of discrete solvent structure inside the loop can be neglected. We show that a pronounced entropic contribution is encountered as the discrete clustering of solvent molecules inside the loop affects the conformations of the chain, forcing the orientation of individual residues. An algorithm for RNA structure prediction incorporating such effects is implemented and tested.

引用

页码：460 / 464

页数：5

共 11 条

[1] SLOW RELAXATIONAL PROCESSES IN THE MELTING OF LINEAR BIO-POLYMERS - A THEORY AND ITS APPLICATION TO NUCLEIC-ACIDS [J].