INDUCTION, ACTIVATION AND INHIBITION OF EPOXIDE HYDRASE - ANOMALOUS PREVENTION OF CHLOROBENZENE-INDUCED HEPATOTOXICITY BY AN INHIBITOR OF EPOXIDE HYDRASE

被引：118

作者：

OESCH, F

JERINA, DM

DALY, JW

RICE, JM

机构：

[1] NIAMDD,BETHESDA,MD 20014

[2] NCI,BETHESDA,MD 20014

来源：

CHEMICO-BIOLOGICAL INTERACTIONS | 1973年 / 6卷 / 03期

关键词：

D O I：

10.1016/0009-2797(73)90071-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：189 / 202

页数：14

共 26 条

[1]

BEUTLER E, 1963, J LAB CLIN MED, V61, P882

[2] POSSIBLE MECHANISM OF LIVER NECROSIS CAUSED BY AROMATIC ORGANIC COMPOUNDS [J].

BRODIE, BB ;

REID, WD ;

CHO, AK ;

SIPES, G ;

KRISHNA, G ;

GILLETTE, JR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1971, 68 (01) :160-&

[3] INDUCED SYTHESIS OF OXIDATIVE ENZYMES IN LIVER MICROSOMES BY POLYCYCLIC HYDROCARBONS AND DRUGS [J].

CONNEY, AH ;

BURNS, JJ .

ADVANCES IN ENZYME REGULATION, 1963, 1 :189-214

[4] A SIMPLE RADIOMETRIC ASSAY FOR MICROSOMAL ARYL HYDROXYLASE ACTIVITY [J].

DALY, JW .

ANALYTICAL BIOCHEMISTRY, 1970, 33 (02) :286-&

[5] IN-VITRO TRANSFORMATION OF RODENT CELLS BY K-REGION DERIVATIVES OF POLYCYCLIC HYDROCARBONS (TISSUE CULTURE/EPOXIDES/CARCINOGENS/DIOLS/PHENOLS) [J].

GROVER, PL ;

SIMS, P ;

HUBERMAN, E ;

MARQUARDT, H ;

KUROKI, T ;

HEIDELBERGER, C .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1971, 68 (06) :1098-+

[6] ROLE OF ARENE OXIDE-OXEPIN SYSTEM IN METABOLISM OF AROMATIC SUBSTRATES .I. IN VITRO CONVERSION OF BENZENE OXIDE TO A PREMERCAPTURIC ACID AND A DIHYDRODIOL [J].

JERINA, D ;

DALY, J ;

WITKOP, B ;

ZALTZMAN.P ;

UDENFRIE.S .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1968, 128 (01) :176-&

[7] 1,2-NAPHTHALENE OXIDE AS AN INTERMEDIATE IN MICROSOMAL HYDROXYLATION OF NAPHTHALENE [J].

JERINA, DM ;

DALY, JW ;

WITKOP, B ;

ZALTZMAN.P ;

UDENFRIEND, S .

BIOCHEMISTRY, 1970, 9 (01) :147-+

[8] DEUTERIUM MIGRATION DURING ACID-CATALYZED DEHYDRATION OF 6-DEUTERIO-5,6-DIHYDROXY-3-CHLORO-1,3-CYCLOHEXADIENE A NONENZYMATIC MODEL FOR NIH SHIFT [J].

JERINA, DM ;

DALY, JW ;

WITKOP, B .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1967, 89 (21) :5488-&

[9] SYNTHESIS OF 1-ARYLIMIDAZOLES, A NEW CLASS OF STEROID HYDROXYLATION INHIBITORS [J].

JOHNSON, AL ;

KAUER, JC ;

SHARMA, DC ;

DORFMAN, RI .

JOURNAL OF MEDICINAL CHEMISTRY, 1969, 12 (06) :1024-&

[10]

JOLLOW D, 1971, PHARMACOLOGIST, V13, P288

← 1 2 3 →