DISTRIBUTION OF BRAIN MONOAMINES IN LEFT-HANDED AND RIGHT-HANDED MICE INJECTED WITH BACILLUS-CALMETTE-GUERIN

被引：4

作者：

DELEPLANQUE, B ^{[1
]}

DELRUE, C ^{[1
]}

VITIELLO, S ^{[1
]}

NEVEU, PJ ^{[1
]}

机构：

[1] UNIV BORDEAUX 2,INSERM,U259,F-33077 BORDEAUX,FRANCE

来源：

INTERNATIONAL JOURNAL OF NEUROSCIENCE | 1993年 / 73卷 / 3-4期

关键词：

BRAIN MONOAMINES; BRAIN ASYMMETRY; BACILLUS CALMETTE-GUERIN; NEUROIMMUNOMODULATION;

D O I：

10.3109/00207459308986677

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Concentrations of brain monoamines from various cerebral structures were determined in ri ht and left sides of the brain from female mice selected for paw preference and injected or not with BCG 8 weeks before. BCG-induced changes in brain monoamine distribution in prefrontal cortex, medial hypothalamus and brain stem were only observed in right-handers. In the posterior hypothalamus, even though there was no BCG effect, norepinephrine asymmetry observed in right-handed controls was suppressed after BCG-injection. Moreover, BCG-induced brain monoamine changes in right-handers mainly involved the right hemisphere except the NE decrease in brain stem which was left-sided. This work demonstrates that the injection of BCG leads to long lasting asymmetrical changes in brain monoamine distribution that furthermore depend on behavioral lateralization of mice.

引用

页码：287 / 298

页数：12

共 27 条

[1] ASYMMETRIC DISTRIBUTION OF BRAIN MONOAMINES IN LEFT-HANDED AND RIGHT-HANDED MICE [J].