ANTIBIOTICS FROM BASIDIOMYCETES .45. CALOPOROSIDE, A NEW INHIBITOR OF PHOSPHOLIPASES-C FROM CALOPORUS-DICHROUS (FR) RYV

被引：27

作者：

WEBER, W ^{[1
]}

SCHU, P ^{[1
]}

ANKE, T ^{[1
]}

VELTEN, R ^{[1
]}

STEGLICH, W ^{[1
]}

机构：

[1] UNIV MUNICH, DEPT ORGAN CHEM, D-80333 MUNICH, GERMANY

来源：

JOURNAL OF ANTIBIOTICS | 1994年 / 47卷 / 11期

关键词：

D O I：

10.7164/antibiotics.47.1188

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A new salicylic acid derivative, caloporoside, was isolated from fermentations of Caloporus dichrous. Its structure was elucidated by a combination of chemical and spectroscopic methods. Caloporoside exhibits weak antibacterial and antifungal activities and is a quite selective inhibitor of phospholipase C isolated from pig brain (Ki 12, 3 mu M).

引用

页码：1188 / 1194

页数：7

共 15 条

[1]

APPLETON HD, 1953, J BIOL CHEM, V205, P803

[2]

Bergmeyer H.U., 1984, METHODDS ENZYMATIC A, P52

[3] STUDY OF C-13H COUPLING-CONSTANTS IN HEXOPYRANOSES [J].