MORPHOLOGICAL AND MECHANICAL-PROPERTIES OF SMALL MESENTERIC-ARTERIES AND VEINS IN SPONTANEOUSLY HYPERTENSIVE RATS

被引:19
作者
AALKJAER, C
MULVANY, MJ
机构
[1] Institute of Biophysics, University of Aarhus
来源
ACTA PHYSIOLOGICA SCANDINAVICA | 1979年 / 107卷 / 04期
关键词
arteries; Morphology; spontaneously hypertensive rats; veins;
D O I
10.1111/j.1748-1716.1979.tb06480.x
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Segments of small mesenteric arteries (—150 μm lumen diameter) and of corresponding veins were taken from 5‐month‐old spontaneously hypertensive rats (SHR) and from age matched Wistar Kyoto (WKY) controls. The segments were mounted on a myograph which enabled their mechanical and morphological parameters to be investigated simultaneously. Compared with the WKY arteries the lumen diameter of the SHR arteries was smaller while the media thickness and active wall tension response were greater. On the other hand there were no differences between the corresponding veins from SHR and WKY animals although, compared with the arteries, the veins had a greater lumen diameter, a smaller media thickness and a smaller tension response. The findings suggest that the morphological and mechanical differences seen in arteries from SHR are not found on the venous side. © 1979 Scandinavian Physiological Society
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页码:309 / 312
页数:4
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