SYNTHESIS OF SAMANINE

被引：4

作者：

CRISTOFOLI, WA

BENN, M

机构：

[1] Chemistry Department, University of Calgary, Calgary

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1991年 / 08期

关键词：

D O I：

10.1039/p19910001825

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The salamander alkaloid samanine (3-aza-A-homo-5-beta-androstan-16-beta-ol) has been synthesized in 10 steps from testosterone acetate in 17% overall yield, the transposition of the oxygen functionality from C-17 to C-16 being achieved by an elimination-hydroboration-oxidation sequence, and the A-ring expansion and insertion of nitrogen via a Schmidt reaction.

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页码：1825 / 1831

页数：7

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