REGIOSELECTIVE AND STEREOSELECTIVE RING-OPENING OF EPOXIDES WITH AMIDE CUPRATE REAGENTS

被引：69

作者：

YAMAMOTO, Y

ASAO, N

MEGURO, M

TSUKADA, N

NEMOTO, H

SADAYORI, N

WILSON, JG

NAKAMURA, H

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1993年 / 15期

关键词：

D O I：

10.1039/c39930001201

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Amide cuprate reagents attack the less hindered carbon atom of epoxides to give 1,2-amino alcohols in good yields; this procedure is applied to the synthesis of an aziridine alcohol bearing a carborane framework which is a potentially useful B-10 carrier for boron neutron capture therapy.

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页码：1201 / 1203

页数：3

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