CHROMOSOME SIZE-DEPENDENT CONTROL OF MEIOTIC RECOMBINATION

被引：146

作者：

KABACK, DB

GUACCI, V

BARBER, D

MAHON, JW

机构：

[1] Department of Microbiology and Molecular Genetics, Graduate School of Biomedical Sciences, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark, NJ 07103

[2] Department of Embryology, Carnegie Institution of Washington, Baltimore

来源：

SCIENCE | 1992年 / 256卷 / 5054期

关键词：

D O I：

10.1126/science.1566070

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Smaller chromosomes have higher rates of meiotic reciprocal recombination (centimorgans per kilobase pair) than larger chromosomes. This report demonstrates that decreasing the size of Saccharomyces cerevisiae chromosomal DNA molecules increases rates of meiotic recombination and increasing chromosome size decreases recombination rates. These results indicate that chromosome size directly affects meiotic reciprocal recombination.

引用

页码：228 / 232

页数：5

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