THE USE OF HPLC TO EVALUATE THE VARIATIONS OF BLOOD CORONARY ADENOSINE LEVELS DURING PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY

被引：20

作者：

GUIEU, R ^{[1
]}

PAGANELLI, F ^{[1
]}

SAMPIERI, F ^{[1
]}

BECHIS, G ^{[1
]}

LEVY, S ^{[1
]}

ROCHAT, H ^{[1
]}

机构：

[1] CHU NORD,SERV CARDIOL,F-13015 MARSEILLE,FRANCE

来源：

CLINICA CHIMICA ACTA | 1994年 / 230卷 / 01期

关键词：

ADENOSINE; ANGIOPLASTY; ISCHEMIA;

D O I：

10.1016/0009-8981(94)90089-2

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Although it is well established that adenosine is released during acute ischemia, little is known of the behaviour of adenosine levels following treatment of coronary lesion by percutaneous transluminal coronary angioplasty (PTCA). Using high performance liquid chromatography, we measured intracoronary adenosine levels before and 5 min after PTCA in ten patients with one-vessel disease and a significant (> 70%) coronary stenosis. Adenosine levels decrease in all patients after PTCA. Nevertheless, more studies are now necessary to evaluate the possible predictive value (with regard to restenosis) of coronary adenosine levels after PTCA.

引用

页码：63 / 68

页数：6

共 36 条

[1] CARDIAC NUCLEOTIDES IN HYPOXIA - POSSIBLE ROLE IN REGULATION OF CORONARY BLOOD FLOW [J].