SYNTHESIS AND CHARACTERIZATION OF BIS-ACRIDINE BRIDGED AT POSITIONS 2, 3 OR 4

被引：6

作者：

BOYER, G

GALY, JP

BARBE, J

机构：

[1] UNIV SCI & TECH MARSEILLE,CHIM ORGAN PHYS LAB,F-13397 MARSEILLE 13,FRANCE

[2] FAC PHARM MARSEILLE,ETUD & RECH CHIM THERAPEUT ORGAN & PHYS GRP,F-13385 MARSEILLE 5,FRANCE

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1991年 / 28卷 / 04期

关键词：

D O I：

10.1002/jhet.5570280413

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The preparation of 2,2', 3,3' and 4,4'-bridged bisacridines is described. The method consists in the acylation of 2, 3, or 4-aminoacridines in acetone, as the solvent. Ten bisacridines were isolated and characterized by their H-1 and C-13 nmr parameters. Some of these were tested as potential intercalating agents, but none has shown any activity from this point of view.

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页码：913 / 918

页数：6

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