THE SYNTHESIS OF 7 ALPHA-AMIDOCARBACEPHEMS

被引：6

作者：

BODUROW, CC

LEVY, JN

WIITALA, KW

机构：

[1] Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center Indianapolis

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 30期

关键词：

CARBACEPHALOSPORIN ANTIBIOTICS; 7-ALPHA-AMIDOCARBACEPHALOSPORIN; EPIMERIC CARBACEPHALOSPORINS; CARBACEPHEMS; EPIMERIZATION;

D O I：

10.1016/S0040-4039(00)74239-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Study of compounds related to the first clinically-investigated 7-beta-amidocarbacephem, loracarbef (1), led to the preparation of key 7-alpha-amidocarbacephem derivatives. The synthesis, characterization, and biological properties of these compounds are reported.

引用

页码：4283 / 4286

页数：4

共 12 条

[1]

BODUROW CC, 1989, TETRAHEDRON LETT, V30, P2312

[2] TOTAL SYNTHESIS OF BETA-LACTAM ANTIBIOTICS .4. EPIMERIZATION OF 6(7)-AMINOPENICILLINS AND 6(7)-CEPHALOSPORINS FROM ALPHA TO BETA [J].