Protein kinase C and tumor promoters

被引:65
作者
Jaken, S. [1 ]
机构
[1] W Alton Jones Cell Sci Ctr, Lake Placid, NY 12946 USA
关键词
D O I
10.1016/0955-0674(90)90006-Z
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The complexity of PKC has made it difficult to define the precise biochemical processes associated with the various PKC-related cellular responses observed. In the past year, we have seen progress in complementary approaches that are helping to solve the puzzles. These include purification and characterization of individual isozymes, expression of normal and mutant PKCs, immunolocalization, and identification of specific activators and inhibitors. All of these will be useful in identifying the primary targets of PKC phosphorylation and their function. © 1990.
引用
收藏
页码:192 / 197
页数:6
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