PHYSIOLOGY OF SECRETION OF ACID, PEPSIN, SULFATED POLYSACCHARIDES AND GLYCOPROTEINS BY DOG FUNDIC MUCOSA

被引:13
作者
LEY, R
BREMEN, J
VERBEUSTEL, S
WOUSSENC.MC
DEGRAEF, J
机构
[1] Department of Surgery, Laboratory of Experimental Surgery, Laboratory of Medical Chemistry, Free University of Brussels, Brussels
关键词
Dogs; Gastric juice; Gastric mucosa; Gastrin; Glycoproteins; Histamine; Hydrochloric acid; Mucopolysaccharides; Mucus; Parasympathomimctics;
D O I
10.1159/000196929
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The secretion of acid, pepsin, chondroitin sulfate and glycoproteins from mucus have been studied in four Heidenhain pouch dogs, under basal condition and during stimulation with histamine, a gastrinlike pentapeptide and a cholinergic drug. Histamine and the gastrin analogue stimulate acid and, to a lesser extent, pepsin secretion, and they inhibit mucus secretion; cholinergic stimulation increases the output of acid, chondroitin sulfate, pepsin and glycoproteins of the mucus. No qualitative changes in the secretion of peptic or mucous cells are observed. © 1969 S. Karger AG, Basel.
引用
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页码:113 / +
页数:1
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