PREPHENATE DEHYDROGENASE FROM NEUROSPORA - FEEDBACK ACTIVATION BY PHENYLALANINE

被引：12

作者：

CATCHESIDE, DE

机构：

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1969年 / 36卷 / 04期

关键词：

D O I：

10.1016/0006-291X(69)90355-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Prephenate dehydrogenase, the first enzyme in the tyrosine branch of the aromatic pathway is subject to feedback inhibition by tyrosine and also to activation by phenylalanine. The arrangement of activated steps in aromatic amino acid biosynthesis suggests that control of the aromatic pathway is adapted to supply a greater flux of tyrosine than is required for vegetative growth. Mutation of the structural gene (pt) for chorismate mutase has no effect upon the control functions of prephenate dehydrogenase, indicating that these enzymes are not structurally associated in Neurospora. © 1969.

引用

页码：651 / +

页数：1

共 13 条

[1]

BAKER TI, 1968, GENETICS, V58, P351

[2] TRYPTOPHAN - A FEEDBACK ACTIVATOR FOR CHORISMATE MUTASE FROM NEUROSPORA [J].