4-YEAR FOLLOW-UP OF 24 1ST-EPISODE MANIC PATIENTS

被引：130

作者：

TOHEN, M

WATERNAUX, CM

TSUANG, MT

HUNT, AT

机构：

[1] MCLEAN HOSP,PSYCHOSIS PROGRAM,BELMONT,MA 02178

[2] HARVARD UNIV,SCH MED,DEPT PSYCHIAT,HARVARD PROGRAM PSYCHIAT EPIDEM,BOSTON,MA 02115

[3] BROCKTON W ROXBURY VET ADM CTR,PSYCHIAT SERV,BROCKTON,MA

[4] HARVARD UNIV,SCH MED,DEPT EPIDEMIOL,HARVARD PROGRAM PSYCHIAT EPIDEMIOL,BOSTON,MA 02115

[5] HARVARD UNIV,SCH PUBL HLTH,DEPT BIOSTAT,BOSTON,MA 02115

来源：

JOURNAL OF AFFECTIVE DISORDERS | 1990年 / 19卷 / 02期

关键词：

First episode; Mania; Outcome; Survival analysis;

D O I：

10.1016/0165-0327(90)90012-W

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Twenty-four first-episode manic patients were followed to investigate the 4-year outcome after recovery from a manic episode. Patients had no documented previous manic or depressive episodes. The presence of psychotic features during the index episode and a history of alcoholism were statistically significant predictors of a shorter time in remission. Low occupational status at baseline predicted poor global social adjustment at 4 years. Also, a larger correlation among outcome measures was found at 48 than at 6 months. The importance of controlling for presence of multiple episodes in outcome studies is emphasized. © 1990.

引用

页码：79 / 86

页数：8

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