PURIFICATION OF PTAQUILOSIDE, A CARCINOGEN FROM PTERIDIUM-AQUILINUM

被引:20
作者
OELRICHS, PB [1 ]
NG, JC [1 ]
BARTLEY, J [1 ]
机构
[1] QUEENSLAND UNIV TECHNOL,SCH CHEM,BRISBANE 4001,QLD,AUSTRALIA
关键词
PTERIDIUM AQUILINUM; PTERIDACEAE; PTAQUILOSIDE; UNSTABLE CARCINOGEN; PURIFICATION;
D O I
10.1016/0031-9422(95)00149-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Ptaquiloside, the major carcinogen of bracken fern (Pteridium aquilinum), was isolated in high yield from milled freeze-dried plant material. Because the compound is unstable, a new method was devised to avoid steps which caused loss of activity. Modern multipulse and 2D NMR techniques allowed confirmation of the previously proposed structure, although some assignments were shown to be incorrect.
引用
收藏
页码:53 / 56
页数:4
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