METAL-COMPOUNDS IN THERAPY AND DIAGNOSIS

被引：253

作者：

ABRAMS, MJ ^{[1
]}

MURRER, BA ^{[1
]}

机构：

[1] JOHNSON MATTHEY TECHNOL CTR, READING RG4 9NH, ENGLAND

来源：

SCIENCE | 1993年 / 261卷 / 5122期

关键词：

D O I：

10.1126/science.8102010

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

There is increasing interest in the use of metal-containing compounds in medicine. This review describes several therapeutic applications, such as the use of platinum complexes in cancer chemotherapy, gold compounds in the treatment of arthritis, gallium in hypercalcemia, bismuth in anti-ulcer medication, and sodium nitroprusside in hypertension. The use of metal radionuclides in diagnosis and radiotherapy and the role of paramagnetic metal complexes as contrast agents in magnetic resonance imaging are also discussed.

引用

页码：725 / 730

页数：6

共 56 条

[1]

ADAMSON RH, 1975, CANCER CHEMOTH REP 1, V59, P599

[2]

ALBERT A, 1985, SELECTIVE TOXICITY, P206

[3]

ANGHILERI LJ, 1987, ANTICANCER RES, V7, P1205

[4] SYNTHESIS, STRUCTURE, AND SPECTROSCOPIC PROPERTIES OF BISMUTH CITRATE COMPOUNDS .1. CRYSTAL-STRUCTURES OF K5-X(NH4)X[BI2(CIT)2(HCIT)](H2O)Y (X = 0.25, Y = 13) AND (NH4)8[BI2(CIT)2(HCIT)2(H2O)4](H2O)2 [J].