ULTRASTRUCTURAL CHARACTERIZATION OF GONADOTROPIN-RELEASING-HORMONE (GNRH)-IMMUNOREACTIVE TERMINAL NERVE-CELLS IN THE DWARF GOURAMI

被引：24

作者：

OKA, Y ^{[1
]}

ICHIKAWA, M ^{[1
]}

机构：

[1] TOKYO METROPOLITAN INST NEUROSCI,FUCHU,TOKYO 183,JAPAN

来源：

NEUROSCIENCE LETTERS | 1992年 / 140卷 / 02期

关键词：

GNRH; ELECTRON MICROSCOPY; TERMINAL NERVE; IMMUNOCYTOCHEMISTRY; NONSYNAPTIC RELEASE; EXOCYTOSIS; TELEOST;

D O I：

10.1016/0304-3940(92)90102-D

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Recently we have been studying gonadotropin-releasing hormone (GnRH) cells of the terminal nerve (TN) in the dwarf gourami, which may serve as a good model system for the study of neuromodulator functions. Here we report on the ultrastructural characterization of TN-GnRH cells using postembedding immunoelectron microscopy. The GnRH immunoreactivities could be demonstrated on dense-cored vesicles (DCVs) in cell bodies, fibers and varicosities. However, we could find no evidence of GnRH-immunoreactive synapses which are characterized by active zones. This may suggest that GnRH is released non-synaptically from DCV-containing fiber varicosities and that it exerts its modulatory action on GnRH receptors located on nearby as well as distant target neurons.

引用

页码：200 / 202

页数：3

共 11 条

[1] M-CURRENTS - AN UPDATE [J].