DIETHYL ACETONEDICARBOXYLATE - A PRECURSOR FOR THE SYNTHESIS OF NEW SUBSTITUTED 4-AMINOQUINOLINES AND FUSED 4-AMINOPYRIDINES

The reaction of cyclic enaminonitriles 1 with diethyl acetonedicarboxylate (2) affords fused 4-amino-3-ethoxycarbonyl-2-ethoxycarbonylmethyl-pyridines 4. The course of the reaction and the yield of cyclic products were promoted by tin(IV)chloride. N-substituted diethyl 3-aminoglutaconates 3 seem to be intermediates of the cyclization reaction.