INHIBITION OF HYDROXYMETHYLGLUTARYL-COENZYME-A SYNTHASE BY L-659,699

被引：101

作者：

GREENSPAN, MD

YUDKOVITZ, JB

LO, CYL

CHEN, JS

ALBERTS, AW

HUNT, VM

CHANG, MN

YANG, SS

THOMPSON, KL

CHIANG, YCP

CHABALA, JC

MONAGHAN, RL

SCHWARTZ, RL

机构：

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1987年 / 84卷 / 21期

关键词：

D O I：

10.1073/pnas.84.21.7488

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：7488 / 7492

页数：5

共 32 条

[1] MEVINOLIN - A HIGHLY POTENT COMPETITIVE INHIBITOR OF HYDROXYMETHYLGLUTARYL-COENZYME-A REDUCTASE AND A CHOLESTEROL-LOWERING AGENT [J].

ALBERTS, AW ;

CHEN, J ;

KURON, G ;

HUNT, V ;

HUFF, J ;

HOFFMAN, C ;

ROTHROCK, J ;

LOPEZ, M ;

JOSHUA, H ;

HARRIS, E ;

PATCHETT, A ;

MONAGHAN, R ;

CURRIE, S ;

STAPLEY, E ;

ALBERSSCHONBERG, G ;

HENSENS, O ;

HIRSHFIELD, J ;

HOOGSTEEN, K ;

LIESCH, J ;

SPRINGER, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (07) :3957-3961

[2]

ALBERTS AW, 1974, J BIOL CHEM, V249, P5124

[3] ANTIBIOTIC 1233A - FUNGAL BETA LACTONE [J].

ALDRIDGE, DC ;

GILES, D ;

TURNER, WB .

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1971, (23) :3888-&

[4]

BERGSTROM JD, 1984, J BIOL CHEM, V259, P4548

[5] MEVINOLIN AND COLESTIPOL STIMULATE RECEPTOR-MEDIATED CLEARANCE OF LOW-DENSITY LIPOPROTEIN FROM PLASMA IN FAMILIAL HYPERCHOLESTEROLEMIA HETEROZYGOTES [J].

BILHEIMER, DW ;

GRUNDY, SM ;

BROWN, MS ;

GOLDSTEIN, JL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (13) :4124-4128

[6] SYNTHESIS OF CHLOROMETHYL KETONE DERIVATIVES OF FATTY-ACIDS - THEIR USE AS SPECIFIC INHIBITORS OF ACETOACETYL-COENZYME A THIOLASE, CHOLESTEROL-BIOSYNTHESIS AND FATTY-ACID SYNTHESIS [J].

BLOXHAM, DP ;

CHALKLEY, RA ;

COGHLIN, SJ ;

SALAM, W .

BIOCHEMICAL JOURNAL, 1978, 175 (03) :999-1011

[7]

BROWN MS, 1974, J BIOL CHEM, V249, P789

[8]

BROWN MS, 1978, J BIOL CHEM, V253, P1121

[9]

CHANG TY, 1980, J BIOL CHEM, V255, P5452

[10]

CLINKENBEARD KD, 1975, J BIOL CHEM, V250, P3124

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