LIPOPROTEIN(A) LEVELS IN THE NEPHROTIC SYNDROME

被引：11

作者：

KANNO, H

SAITO, E

FUJIOKA, T

YASUGI, T

机构：

[1] Second Department of Internal Medicine, Nihon University School of Medicine, Tokyo

来源：

INTERNAL MEDICINE | 1992年 / 31卷 / 08期

关键词：

HYPERLIPOPROTEIN(A)EMIA; HYPOALBUMINEMIA;

D O I：

10.2169/internalmedicine.31.1004

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We investigated serum lipoprotein(a) [Lp(a)] levels in 20 patients with the nephrotic syndrome. Lp(a) levels in the nephrotic syndrome patients were significantly higher than those in a control group (30.4 +/- 22.5 vs 10.4 +/- 17.7 mg/dl). Overall, the serum Lp(a) and lipid levels showed no relationship, but on an individual basis the serum Lp(a) level varied with the serum levels of total cholesterol and low density lipoprotein cholesterol in the nephrotic syndrome patients. Our findings suggest that a decrease in serum albumin led to increased hepatic Lp(a) synthesis. It is well known that thrombotic disease supervenes on hypercoagulability in the nephrotic syndrome, so the determination of Lp(a) levels in these patients may provide information which is useful for preventing thrombotic complications.

引用

页码：1004 / 1008

页数：5

共 27 条

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