GAS-PHASE BASICITIES AND PROTON AFFINITIES OF LYSINE AND HISTIDINE MEASURED FROM THE DISSOCIATION OF PROTON-BOUND DIMERS

被引：140

作者：

WU, ZC ^{[1
]}

FENSELAU, C ^{[1
]}

机构：

[1] UNIV MARYLAND,CTR STRUCT BIOCHEM,DEPT CHEM & BIOCHEM,CATONSVILLE,MD 21228

来源：

RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 1994年 / 8卷 / 09期

关键词：

D O I：

10.1002/rcm.1290080923

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Gas-phase basicities and proton affinities of lysine and histidine were measured by the kinetic method. Using low-energy collisional activation to change the effective temperature in the dissociation of proton-bound dimer, proton affinities of lysine and histidine were determined to be 235.3 and 234.0 kcal/mol respectively. A large entropy effect was found for lysine, and thus at temperatures above 300 K, histidine is slightly more basic than lysine. Peptides that contain lysine or histidine are more basic than lysine or histidine. The basicities of these peptides depend on their structures and the internal hydrogen bonding.

引用

页码：777 / 780

页数：4

共 20 条

[1] PROTON AFFINITIES OF LYSINE AND HISTIDINE - A THEORETICAL CONSIDERATION OF THE DISCREPANCY BETWEEN EXPERIMENTAL RESULTS FROM THE KINETIC AND BRACKETING METHODS [J].

BLIZNYUK, AA ;

SCHAEFER, HF ;

AMSTER, IJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (12) :5149-5154

[2] THE ORDER OF PROTON AFFINITIES OF THE 20 COMMON 1-ALPHA-AMINO ACIDS [J].

BOJESEN, G .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (18) :5557-5558

[3]

Bowers M. T., 1979, GAS PHASE ION CHEM

[4]

BREINDAHL T, 1991, 12TH INT MASS SPECTR

[5] CORRELATIONS OF LONE PAIR IONIZATION ENERGIES WITH PROTON AFFINITIES OF AMINO-ACIDS AND RELATED-COMPOUNDS - SITE SPECIFICITY OF PROTONATION [J].

CAMPBELL, S ;

BEAUCHAMP, JL ;

REMPE, M ;

LICHTENBERGER, DL .

INTERNATIONAL JOURNAL OF MASS SPECTROMETRY AND ION PROCESSES, 1992, 117 (1-3) :83-99

[6] COLLISION ENERGY-DEPENDENCE OF PROTON-BOUND DIMER DISSOCIATION - ENTROPY EFFECTS, PROTON AFFINITIES, AND INTRAMOLECULAR HYDROGEN-BONDING IN PROTONATED PEPTIDES [J].

CHENG, XH ;

WU, ZC ;

FENSELAU, C .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (11) :4844-4848

[7] PROTON AFFINITIES OF THE 20 COMMON ALPHA-AMINO-ACIDS [J].

GORMAN, GS ;

SPEIR, JP ;

TURNER, CA ;

AMSTER, IJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (10) :3986-3988

[8] KINETIC AND THERMODYNAMIC CONSIDERATIONS OF THE BRACKETING METHOD - ENTROPY-DRIVEN PROTON-TRANSFER REACTIONS IN A FOURIER-TRANSFORM MASS-SPECTROMETER [J].

GORMAN, GS ;

AMSTER, IJ .

ORGANIC MASS SPECTROMETRY, 1993, 28 (12) :1602-1607

[9] NEW RULES CONCERNING THE FORMATION OF PROTONATED AMINO-ACIDS FROM PROTONATED DIPEPTIDES USING THE PROTON AFFINITY ORDER DETERMINED FROM COLLISIONALLY ACTIVATED DECOMPOSITION SPECTRA [J].

ISA, K ;

OMOTE, T ;

AMAYA, M .

ORGANIC MASS SPECTROMETRY, 1990, 25 (11) :620-628

[10] EVALUATED GAS-PHASE BASICITIES AND PROTON AFFINITIES OF MOLECULES - HEATS OF FORMATION OF PROTONATED MOLECULES [J].

LIAS, SG ;

LIEBMAN, JF ;

LEVIN, RD .

JOURNAL OF PHYSICAL AND CHEMICAL REFERENCE DATA, 1984, 13 (03) :695-808

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