BIOSYNTHETIC-PATHWAY OF THE ASPARAGINE-LINKED OLIGOSACCHARIDES OF GLYCOPROTEINS

被引:41
作者
STANELONI, RJ [1 ]
LELOIR, LF [1 ]
机构
[1] FAC CIENCIAS EXACTAS & NAT BUENOS AIRES,BUENOS AIRES,ARGENTINA
关键词
D O I
10.1016/0968-0004(79)90265-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A dolichyl diphosphate oligosaccharide containing glucose, mannose and N-acetylglucosamine is the precursor of the sugar -moiety of some glycoproteins. Studies of glycoproteins produced by virus-infected cells, using endo-N-acetylglycosaminidase for the liberation of the sugar moiety, have shown that the glucose-containing oligosaccharide is transferred to protein, then the glucose and some mannose residues are removed and acetlyglucosamine, galactose and sialic acid are added. © 1979.
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页码:65 / 67
页数:3
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