IDENTIFICATION OF THE ACTIVE METABOLITES OF THE ISOXAZOLYL-PENICILLINS BY MEANS OF MASS-SPECTROMETRY

被引:15
作者
THIJSSEN, HHW
机构
[1] Department of Pharmacology, Biomedical Centre, Medical Faculty Maastricht, Maastricht
关键词
D O I
10.7164/antibiotics.32.1033
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Electron-impact mass-spectrometry of the methyl esters of the isoxazolylpenicillins and of their active metabolites showed the latter to be formed from their parent compounds by hydroxylation of the 5-methyl group. © 1979, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.
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页码:1033 / 1037
页数:5
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