CHARACTERIZATION OF PHENOLIC GLYCOLIPIDS FROM MYCOBACTERIUM-MARINUM

被引：20

作者：

DOBSON, G

MINNIKIN, DE

BESRA, GS

MALLET, AI

MAGNUSSON, M

机构：

[1] UNIV NEWCASTLE UPON TYNE,DEPT CHEM,NEWCASTLE TYNE NE1 7RU,TYNE & WEAR,ENGLAND

[2] UNIV NEWCASTLE UPON TYNE,DEPT MICROBIOL,NEWCASTLE TYNE NE1 7RU,TYNE & WEAR,ENGLAND

[3] ST THOMAS HOSP,INST DERMATOL,LONDON SE1 7EH,ENGLAND

[4] STATENS SERUM INST,DEPT TUBERCULIN,DK-2300 COPENHAGEN S,DENMARK

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1990年 / 1042卷 / 02期

关键词：

(M. marinum); Methyl-branched fatty acid; Phenolic glycolipid; Phenolphthiocerol; Phenolphthiotriol;

D O I：

10.1016/0005-2760(90)90004-H

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The phenolic glycolipids from two strains of Mycobacterium marinum have been isolated and characterised. The glycolipids from M. marinum MNC 170 were principally glycosides of diacyl C37, C39 and C41, phenolphthiocerols A, but in M. marinum MNC 842, these lipids were accompanied by glycosides of diacyl phenolphthiodiolones A and novel phthiotriols A with the same overall chain-lengths. The main acyl components of the phenolic glycolipids from M. marinum MNC 170 were C26 dimethyl and C27 and C29 trimethyl-branched fatty acids, but in the lipids of M. marinum MNC 842, the C27 trimethyl acid was the only principal component. The sugar composition of all these glycolipids had been previously shown to correspond to 3-O-methylrhamnose. © 1990.

引用

页码：176 / 181

页数：6

共 16 条

[1] BRENNAN PJ, 1988, MICROBIAL LIPIDS, V1, P203
[2] STRUCTURE OF THE MAJOR TRIGLYCOSYL PHENOL-PHTHIOCEROL OF MYCOBACTERIUM-TUBERCULOSIS (STRAIN CANETTI)
DAFFE, M
LACAVE, C
LANEELLE, MA
LANEELLE, G
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1987, 167 (01): : 155 - 160
[3] DAFFE M, 1988, J GEN MICROBIOL, V134, P2049
[4] DOBSON G, 1985, CHEM METHODS BACTERI, P237
[5] FOURNIE JJ, 1987, J BIOL CHEM, V262, P3180
[6] FOURNIE JJ, 1987, J BIOL CHEM, V262, P3174
[7] VARIANTS OF MYCOSIDES CHARACTERIZED BY SUBSTITUTED GLYCOSIDIC RESIDUES IN ACYL CHAINS .1. MASS-SPECTRA OF PERACETYLATED MYCOSIDES G' AND A'
GASTAMBIDEODIER, M
[J]. ORGANIC MASS SPECTROMETRY, 1973, 7 (07): : 845 - 860
[8] VARIANTS OF MYCOSIDES CHARACTERIZED BY GLYCOSIDE RESIDUES SUBSTITUTED BY ACYLATED CHAINS - MYCOLIC NATURE OF MYCOSIDES G'
GASTAMBIDEODIER, M
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1973, 33 (01): : 81 - 86
[9] GASTAMBIDEODIER M, 1967, B SOC CHIM BIOL, V49, P849
[10] GAS-CHROMATOGRAPHY MASS-SPECTROMETRY OF TERT-BUTYLDIMETHYLSILYL ETHERS OF PHTHIOCEROLS AND MYCOCEROSIC ALCOHOLS FROM MYCOBACTERIUM-TUBERCULOSIS
MALLET, AI
MINNIKIN, DE
DOBSON, G
[J]. BIOMEDICAL MASS SPECTROMETRY, 1984, 11 (02): : 79 - 86

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