ASSESSMENT OF QUALITY-OF-LIFE OF PATIENTS WITH SEVERE ISCHEMIA AS A RESULT OF INFRAINGUINAL ARTERIAL OCCLUSIVE DISEASE

被引:113
作者
ALBERS, M [1 ]
FRATEZI, AC [1 ]
DELUCCIA, N [1 ]
机构
[1] UNIV SAO PAULO,DEPT SURG,DIV VASC SURG,SAO PAULO,BRAZIL
关键词
D O I
10.1016/0741-5214(92)90417-7
中图分类号
R61 [外科手术学];
学科分类号
摘要
The purpose of this cohort study was to assess the quality of life of patients with severe ischemia as a result of infrainguinal arterial occlusive disease. Spitzer's QL-INDEX was selected to measure quality of life at baseline and at 3, 6, and 12 months. On the basis of initial treatment, 61 patients were grouped as follows: IC (conservative, n = 31), IR (arterial reconstruction, n = 14), and IA (major amputation, n = 16). After 12 months of follow-up, 48 patients were similarly regrouped according to ultimate treatment as follows: UC (n = 19), UR (n = 9), and UA (n = 20). At 12 months the mean score was significantly higher than the baseline in IC (6.43 vs 3.84, p < 0.0001) as well as IR (5.64 vs 3.57,p < 0.01), but not in IA (4.43 vs 3.62). The QL-INDEX mean score was lower in UA than in UC (4.15 vs 6.58, p < 0.01) or UR (4.15 vs 7.11, p < 0.0001). The correlation between QL-INDEX and an arbitrary scale was also high (r = 0.726, p < 0.001). In conclusion, quality of life of patients with limb ischemia can be confidently assessed, improves during the first year of follow-up if major amputation is avoided, and improves and is sustained by a functioning graft.
引用
收藏
页码:54 / 59
页数:6
相关论文
共 13 条
  • [1] Mor, Cancer patients' quality of life over the disease course: lessons from the real world, J Chron Dis, 40, pp. 535-544, (1987)
  • [2] O'Young, McPeek, Quailty of life variables in surgical trials, J Chron Dis, 40, pp. 513-522, (1987)
  • [3] Fletcher, Hunt, Bulpitt, Evaluation of quality of life in clinical trials of cardiovascular disease, J Chron Dis, 40, pp. 557-566, (1987)
  • [4] De Luccia, Pinto, Bruneli, Et al., Cir Vasc Ang, Reabilitação em doentes amputados por doença arterial periférica, 1, pp. 29-33, (1985)
  • [5] Spitzer, Dobson, Hall, Et al., Measuring the quality of life of cancer patients a concise QL-INDEX for use by physicians, Journal of Chronic Diseases, 34, pp. 885-897, (1981)
  • [6] Rutherford, Flanigan, Gupta, Et al., Suggested standards dealing with lower extremity ischemia, Journal of Vascular Surgery, 4, pp. 80-94, (1986)
  • [7] Wallenstein, Zucker, Fleiss, Some statistical methods useful in circulation research, Circ Res, 47, pp. 1-9, (1980)
  • [8] Siegel, Estatística não-paramétrica para as ciências do comportamento, pp. 228-240, (1975)
  • [9] Spitzer, State of science 1986: quality, of life and functional status as target variables for research, J Chron Dis, 40, pp. 465-471, (1987)
  • [10] Hosie, Kockelberg, Newbury-Ecob, Callum, Nash, A retrospective review of the outcome of patients over 70 years of age considered for vascular reconstruction in a district general hospital, Eur J Vase Surg, 4, pp. 313-315, (1990)