EFFECT OF MODIFICATION OF ONE HISTIDINE RESIDUE ON THE ENZYMATIC AND PHARMACOLOGICAL PROPERTIES OF A TOXIC PHOSPHOLIPASE-A2 FROM NAJA-NIGRICOLLIS SNAKE-VENOM AND LESS TOXIC PHOSPHOLIPASES-A2 FROM HEMACHATUS-HAEMACHATUS AND NAJA-NAJA-ATRA SNAKE-VENOMS

被引：75

作者：

CONDREA, E ^{[1
]}

FLETCHER, JE ^{[1
]}

RAPUANO, BE ^{[1
]}

YANG, CC ^{[1
]}

ROSENBERG, P ^{[1
]}

机构：

[1] NATL TSINGHUA UNIV,INST MOLEC BIOL,HSINCHU,TAIWAN

来源：

TOXICON | 1981年 / 19卷 / 01期

关键词：

D O I：

10.1016/0041-0101(81)90118-5

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

收藏

页码：61 / 71

页数：11

相关论文

共 27 条

[1] ISOLATION AND CHARACTERIZATION OF PRE-SYNAPTICALLY ACTING NEUROTOXINS FROM VENOM OF BUNGARUS SNAKES
ABE, T
ALEMA, S
MILEDI, R
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1977, 80 (01): : 1 - 12
[2] SPECIFICITY REVERSAL IN PHOSPHOLIPASE A2 HYDROLYSIS OF LIPID MIXTURES
ADAMICH, M
DENNIS, EA
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1978, 80 (02) : 424 - 428
[3] BARTLETT GR, 1959, J BIOL CHEM, V234, P466
[4] BLIGH EG, 1959, CAN J BIOCHEM PHYS, V37, P911
[5] BOFFA M C, 1979, Toxicon, V17, P11
[6] STUDIES ON STATUS OF TYROSYL RESIDUES IN COBROTOXIN
CHANG, CC
YANG, CC
HAMAGUCHI, K
NAKAI, K
HAYASHI, K
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1971, 236 (01) : 164 - +
[7] DEMONSTRATION OF PHOSPHOLIPID SPLITTING AS FACTOR RESPONSIBLE FOR INCREASED PERMEABILITY AND BLOCK OF AXONAL CONDUCTION INDUCED BY SNAKE VENOM
CONDREA, E
ROSENBER.P
DETTBARN, WD
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1967, 135 (04) : 669 - +
[8] COMPARISON OF A RELATIVELY TOXIC PHOSPHOLIPASE-A2 FROM NAJA-NIGRICOLLIS SNAKE-VENOM WITH THAT OF A RELATIVELY NON-TOXIC PHOSPHOLIPASE-A2 FROM HEMACHATUS-HAEMACHATUS SNAKE-VENOM .1. ENZYMATIC-ACTIVITY ON FREE AND MEMBRANE-BOUND SUBSTRATES
CONDREA, E
YANG, CC
ROSENBERG, P
[J]. BIOCHEMICAL PHARMACOLOGY, 1980, 29 (11) : 1555 - 1563
[9] CRESTFIELD AM, 1963, J BIOL CHEM, V238, P622
[10] RELATION BETWEEN NON-ESTERIFIED FATTY ACIDS IN PLASMA AND THE METABOLISM OF GLUCOSE
DOLE, VP
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1956, 35 (02) : 150 - 154