STEREOSELECTIVE SYNTHESIS OF AN ISOQUINOLINOPYRROLIDINONE BY ACYLIMINIUM ION CYCLIZATION OF CHIRAL HYDROXYLACTAMS

被引：20

作者：

LEE, YS ^{[1
]}

KANG, DW ^{[1
]}

LEE, SJ ^{[1
]}

PARK, H ^{[1
]}

机构：

[1] HANKOOK UNIV FOREIGN STUDIES, DEPT CHEM, SEOUL 130791, SOUTH KOREA

来源：

SYNTHETIC COMMUNICATIONS | 1995年 / 25卷 / 13期

关键词：

D O I：

10.1080/00397919508015871

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Studies on the stereoselective synthesis of a pyrrolidinoisoquinoline derivative using acyliminium ion cyclization of hydroxylactams are described. Cyclization reaction of chiral hydroxylactams 2a similar to c, derived from (L)-tartaric acid and phenethylamine, afforded one diastereomer 3 under a variety of acidic conditions in moderate to good yields.

引用

页码：1947 / 1956

页数：10

共 16 条

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