STUDIES USING RADIOISOTOPES .2. HYDROXYLATION-INDUCED MIGRATION OF TRITIUM DURING BIOSYNTHESIS OF FUROQUINOLINE ALKALOIDS

被引:8
作者
HALL, CR
PRAGER, RH
机构
[1] Organic Chemistry Department, University of Adelaide, Adelaide, SA, 5001
基金
澳大利亚研究理事会;
关键词
D O I
10.1071/CH9692437
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
[4-T]Anthranilic acid has been synthesized and administered to Acronychia baueri. The furoquinoline alkaloids skimmianine (I) and acronidine (II) have considerable residual radioactivity, but acronycidine (IV) is only feebly radioactive. A partly specific “N.I.H. shift” is postulated and its implication to the order of introduction of hydroxyl groups in vivo is discussed. © 1969, CSIRO. All rights reserved.
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页码:2437 / &
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