TUMOR INDUCTION IN DEVELOPING FROG KIDNEYS BY A ZONAL CENTRIFUGE PURIFIED FRACTION OF FROG HERPES-TYPE VIRUS

被引：59

作者：

MIZELL, M

TOPLIN, I

ISAACS, JJ

机构：

来源：

SCIENCE | 1969年 / 165卷 / 3898期

关键词：

D O I：

10.1126/science.165.3898.1134

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Injection of frog embryos (Rana pipiens) with a zonal centrifuge purified fraction of herpes-type virus (prepared from virus-containing Lucké tumors) resulted in a high incidence of kidney tumors. This partially purified oncogenic fraction contained a high concentration of an enveloped form of the frog herpes-type virus (adjacent fractions lacked this particle and were not oncogenic), which suggests that this form of the virus plays a role in the genesis of the Lucké tumor.

引用

页码：1134 / +

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