ALPHA-HOMONOJIRIMYCIN AND 2,5-DIHYDROXYMETHYL-3,4-DIHYDROXY-PYRROLIDINE - ALKALOIDAL GLYCOSIDASE INHIBITORS IN THE MOTH URANIA-FULGENS

被引:34
作者
KITE, GC
HORN, JM
ROMEO, JT
FELLOWS, LE
LEES, DC
SCOFIELD, AM
SMITH, NG
机构
[1] UNIV LONDON WYE COLL,DEPT BIOCHEM & BIOL SCI,ASHFORD TN25 5AH,KENT,ENGLAND
[2] SMITHSONIAN TROP RES INST,BALBOA,PANAMA
[3] ORGANON INC,DEPT CLIN DEV,W ORANGE,NJ 07052
[4] UNIV S FLORIDA,DEPT BIOL,TAMPA,FL 33620
关键词
1,5-dideoxy-1,5-imino-D-mannitol (DMJ); 2,6-dideoxy-2,6-imino-d-glycero-l-gulo-heptitol (α-homonojirimycin); 2R; 5R-dihydroxymethyl-3R; 4R-dihydroxypyrrolidine; (DMDP); alkaloids; Euphorbiaceac; glycosidase inhibitors; Omphalea diandra; Urania fulgens; Uraniidae;
D O I
10.1016/0031-9422(90)89020-A
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Adults, pupae and eggs of the neotropical moth, Urania fulgens, contain a-homonojirimycin and 2,5-dihydroxymethyl-3,4-dihydroxypyrrolidine, two of the alkaloidal glycosidase inhibitors that occur in the larval foodplant, Omphalea diandra. This is the first report of the occurrence of such compounds in animals. © 1990.
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页码:103 / 105
页数:3
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