PROGRAMMED CELL-DEATH IN CAENORHABDITIS-ELEGANS

被引：321

作者：

HENGARTNER, MO ^{[1
]}

HORVITZ, HR ^{[1
]}

机构：

[1] MIT, HOWARD HUGHES MED INST, DEPT BIOL, CAMBRIDGE, MA 02139 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1994年 / 4卷 / 04期

关键词：

D O I：

10.1016/0959-437X(94)90076-F

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Programmed cell death in the nematode Caenorhabditis elegans requires the activities of the genes ced-3 and ced-4 and is antagonized by the activity of the gene ced-9. Cloning of these C. elegans genes has shown that two of them encode proteins with similarity to vertebrate cell death genes and has revealed that nematodes and mammals share a common pathway for programmed cell death.

引用

页码：581 / 586

页数：6

共 45 条

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