EFFICACY OF GLOVES IN REDUCING BLOOD VOLUMES TRANSFERRED DURING SIMULATED NEEDLESTICK INJURY

被引:128
作者
MAST, ST
WOOLWINE, JD
GERBERDING, JL
机构
[1] SAN FRANCISCO GEN HOSP,MED SERV 5H-22,1001 POTRERO AVE,SAN FRANCISCO,CA 94110
[2] UNIV CALIF SAN FRANCISCO,DEPT MED & INFECT DIS,SAN FRANCISCO,CA 94143
关键词
D O I
10.1093/infdis/168.6.1589
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
This study was designed to evaluate factors that affect blood volumes transferred to skin during simulated needlestick injuries in an in vitro paper prefilter model and an ex vivo porcine tissue model. The effect of needle type and size, penetration depth, and glove use on the volume of radiolabeled blood transferred was determined in each model. Blood volumes ranged from 0.47 +/- 0.26 muL (30-gauge needle, 0.5-cm depth, in vitro model) to 5.88 +/- 1.45 muL (18-gauge needle, 2.0-cm depth, in vitro model). Needle size and penetration depth were significantly associated with transfer volume. Glove material reduced the transferred blood volume by 46%-86% in both models. Transfer volumes were within the same order of magnitude for all conditions. Hence, virus titer in the source blood may be a better predictor of needlestick infectivity than is exposure volume. Regardless, gloves may exert some protective effect and should be worn whenever needles are handled.
引用
收藏
页码:1589 / 1592
页数:4
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