INVESTIGATION OF A CASE OF PREDNISOLONE MALABSORPTION

被引：9

作者：

MANT, TGK

机构：

[1] Clinical Pharmacology Department, Guy's Hospital, Medical School

来源：

POSTGRADUATE MEDICAL JOURNAL | 1979年 / 55卷 / 644期

关键词：

D O I：

10.1136/pgmj.55.644.421

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Malabsorption of prednisolone administered as enteric coated tablets was suspected following therapeutic failure in an asthmatic. This was investigated by cortisol estimation and a Synacthen test and substantiated by the demonstration of abnormally low absorption of prednisolone from these tablets which nevertheless were normally absorbed by a volunteer. The absorption of prednisolone from conventional tablets in this patient was normal. © 1979 The Fellowship of Postgraduate Medicine.

引用

页码：421 / 422

页数：2

共 5 条

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MORRISON, PJ ;

BRADBROOK, ID ;

ROGERS, HJ .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1977, 4 (05) :597-603

[2]

NIMMO W S, 1976, Clinical Pharmacokinetics, V1, P189, DOI 10.2165/00003088-197601030-00002

[3]

PARSONS RL, 1977, CLIN PHARMACOKINET, V2, P45, DOI 10.2165/00003088-197702010-00004

[4] EFFECT OF PREDNISONE TREATMENT ON HALF-LIFE OF INTRAVENOUS HYDROCORTISONE [J].

SHENFIELD, GM ;

PATERSON, JW ;

COSTELLO, JF ;

IJADUOLA, O .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1974, 1 (03) :237-240

[5]

WEST HJ, 1959, BRIT MED J, V1, P680

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