CYCLOADDITION-OXIDATIVE CLEAVAGE PATHWAYS TO 14-BETA-FORMYL-19-NORSTEROIDS

被引：2

作者：

BULL, JR

HOADLEY, C

机构：

[1] Department of Chemistry, University of Cape Town, Rondebosch

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 33期

关键词：

D O I：

10.1016/0040-4039(94)88107-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cycloaddition of 3-methoxyestra-1,3,5(10),14,16-pentaen-17-yl acetate 1 with methyl propiolate, followed by chemoselective modification of the cycloadduct, furnishes intermediates for reduction-oxidative cleavage reaction sequences, leading to the 14 beta-formyl analogue of estrone and related 14 beta-formyl-19-norsteroids.

引用

页码：6171 / 6174

页数：4

共 5 条

[1]

ATWAL KS, 1982, HETEROCYCLES, V19, P641

[2] CYCLOADDITION OF PHENYL VINYL SULFONE TO 3-METHOXY-16-METHYLESTRA-1,3,5(10),14,16-PENTAEN-17-YL ACETATE - SYNTHESIS OF 14-FUNCTIONALIZED 19-NORPREGNANE DERIVATIVES [J].