ESCHERICHIA-COLI K ANTIGEN IN RELATION TO SERUM-INDUCED LYSIS AND PHAGOCYTOSIS

被引：28

作者：

VANDIJK, WC ^{[1
]}

VERBRUGH, HA ^{[1
]}

PETERS, R ^{[1
]}

VANDERTOL, ME ^{[1
]}

PETERSON, PK ^{[1
]}

VERHOEF, J ^{[1
]}

机构：

[1] UNIV MINNESOTA,DEPT MED,MINNEAPOLIS,MN 55455

来源：

JOURNAL OF MEDICAL MICROBIOLOGY | 1979年 / 12卷 / 01期

关键词：

D O I：

10.1099/00222615-12-1-123

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The presence of capsular polysaccharides (K antigens) and their relation to phagocytosis and sensitivity to the lytic action of serum of 26 strains of E. coli isolated from stools of healthy volunteers and from blood cultures were studied. Four of 12 strains isolated from stool cultures and 12 (86%) of the 14 strains isolated from blood cultures possessed K antigen. Three of the 12 strains isolated from stool cultures and seven of the 14 isolated from blood cultures were resistant to uptake by polymorphonuclear leucocytes; these resistant strains contained large amounts of K antigen. By contrast 10 strains, three with low amounts of K antigen and seven without detectable amounts of K antigen, were readily phagocytosed. Thus it appears that K antigen renders E. coli resistant to phagocytosis. Only four (15%) of the 26 strains were sensitive to serum lysis and there was no correlation between the presence of K antigen and the resistance to serum lysis.

引用

页码：123 / 130

页数：8

共 23 条

[1] INTERACTION OF ESCHERICHIA-COLI STRAINS WITH HUMAN-SERUM - LACK OF RELATIONSHIP TO K1 ANTIGEN [J].