OUTCOME OF PREGNANCY AFTER 1ST TRIMESTER EXPOSURE TO H-2-RECEPTOR ANTAGONISTS

被引：14

作者：

KOREN, G

ZEMLICKIS, DM

机构：

[1] The Motherisk Clinic, Division of Clinical Pharmacology, Department of Pediatrics, The Research Institute, The Hospital for Sick Children, Toronto, Ontario

来源：

AMERICAN JOURNAL OF PERINATOLOGY | 1991年 / 8卷 / 01期

关键词：

D O I：

10.1055/s-2007-999336

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

H-2 antagonists are widely prescribed medications and are often consumed by women who are unaware of being pregnant. In 23 cases reported to the Motherisk program there were two spontaneous abortions, two therapeutic abortions, 18 normal births, and one infant with a large hemangioma of the upper right eyelid. The hemangioma was removed without incident. Our data suggest that cimetidine and ranitidine may not be teratogenic risk in humans.

引用

页码：37 / 38

页数：2

共 7 条

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[4] Koren G., MacLeod S.M., Monitoring and avoiding drug and chemical teratogenicity, Can Med Assoc J, 135, pp. 1079-1081, (1986)
[5] Koren G., Bologa M., Long D., Pellegrini E., Shear N., The perception of teratogenic risk by pregnant women exposed to drugs and chemicals in the first trimester, Am J Obstet Gynecol (in press)
[6] Briggs, Freedman, Yaffe, Drugs in Pregnancy and Breastfeeding, (1986)
[7] Koren G., Retinoid embryopathy, N Engl J Med, 315, (1986)

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