OYSTER MUSHROOM (PLEUROTUS-OSTREATUS) REDUCES THE ACTIVITY OF 3-HYDROXY-3-METHYLGLUTARYL COA REDUCTASE IN RAT-LIVER MICROSOMES

被引：31

作者：

BOBEK, P ^{[1
]}

HROMADOVA, M ^{[1
]}

OZDIN, L ^{[1
]}

机构：

[1] SLOVAK ACAD SCI,INST EXPTL ENDOCRINOL,BRATISLAVA,SLOVAKIA

来源：

EXPERIENTIA | 1995年 / 51卷 / 06期

关键词：

OYSTER MUSHROOM (PLEUROTUS OSTREATUS); CHOLESTEROL; SERUM; LIPOPROTEINS; LIVER; HMG-COA REDUCTASE;

D O I：

10.1007/BF02128749

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The effect of dried oyster mushroom (Pleurotus ostreatus) on cholesterol (C) content in serum, in lipoproteins and in liver, and on the activity of 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase in liver microsomes, was studied in male rats (strain Wistar, initial body weight 75 g) fed on low-cholesterol (9 mg/100g) and high-cholesterol (0.3%) diets. Addition of 5% oyster mushroom to both diets reduced significantly the C-content in serum (by 30%), in very-low- and low-density lipoproteins (in a 1:1 ratio to the decrease of total serum C) and in liver (by 50%), as well as the activity of HMG-CoA reductase (by more than 30%).

引用

页码：589 / 591

页数：3

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