ATTEMPTS TO USE CARBODIIMIDE (EDCI) TO CROSS-LINK HEMOGLOBIN FOR TRANSFUSIONS

被引：4

作者：

LABRUDE, P

TEISSEIRE, B

VIGNERON, C

机构：

[1] CTR HOSP UNIV NANCY,CTR REG TRANSFUS SANGUINE & HEMATOL,F-54000 VANDOEUVRE NANCY,FRANCE

[2] CTR HOSP UNIV HENRI MONDOR,INSERM,U138,F-94010 CRETEIL,FRANCE

[3] CTR HOSP UNIV HENRI MONDOR,SERV EXPLORAT FONCTIONNELLES,F-94010 CRETEIL,FRANCE

来源：

EXPERIENTIA | 1979年 / 35卷 / 05期

关键词：

D O I：

10.1007/BF01960397

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The polymerization of hemoglobin for use as a blood substitute and an oxygen carrier would be of interest because high-mol. wt macromolecules would have a longer vascular retention time than the monomer. We found that the molecules resulting from the treatment of hemoglobin with ethyldimethylaminopropylcarbodiimide did not have a higher mol. wt than free hemoglobin and also had a dissociation curve resembling that of monomers, but seemed more stable. © 1979 Birkhäuser Verlag.

引用

页码：682 / 683

页数：2

共 8 条

[1]

Evelyn KA, 1938, J BIOL CHEM, V126, P655

[2]

HOROWITZ B, 1977, 9TH ANN SCI S WASH

[3]

LABIE D, 1971, NOUV REV FR HEMATOL, V11, P57

[4]

LABRUDE P, 1977, AGRESSOLOGIE, V18, P21

[5]

LABRUDE P, 1976, THESIS NANCY

[6]

MOK W, 1975, FED PROC, V34, P1458

[7] EVALUATION OF A STROMA-FREE HEMOGLOBIN SOLUTION FOR USE AS A PLASMA EXPANDER [J].

RABINER, SF ;

HELBERT, JR ;

LOPAS, H ;

FRIEDMAN, LH .

JOURNAL OF EXPERIMENTAL MEDICINE, 1967, 126 (06) :1127-+

[8]

TEISSEIRE B, 1977, B EUR PHYSIOPATH RES, V13, P261

← 1 →