NEW OXYGEN SENSORS AND THEIR APPLICATION TO BIOSENSING

被引:143
作者
PAPKOVSKY, DB
机构
[1] Department of Biosensors, Research Centre of Molecular Diagnostics, 113149 Moscow
关键词
OXYGEN SENSORS; FIBER OPTICS; PHOSPHORESCENCE; LUMINESCENCE; LIFETIME-BASED SENSING; PORPHYRINS; LANGMUIR-BLODGETT; SULFUR DIOXIDE;
D O I
10.1016/0925-4005(95)01685-6
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Recent developments in quenched-luminescence oxygen sensors based on application of phosphorescent probes are discussed. They include the development of new oxygen probes on the basis of the derivative of platinum octaethylporphine, which have improved working characteristics and high compatibility with light-emitting diode excitation. New oxygen probes make it possible to construct compact, simple and cheap measurement device(s) using customized semiconductor optoelectronics. A working prototype fibre-optic intensity-based oxygen sensor was developed. Creation of such a device and its study proved the possibility of its further transformation into a device realizing the lifetime-based sensing approach. Several new applications of phophorescent sensing materials are presented. They cover enzymatic systems and a 'cytosensor' arrangement on the basis of the lifetime-based fibre-optic oxygen sensor, and long-decay phosphorescent coating for sensing in the law oxygen range. Special emphasis is placed on the development of new phosphorescent Langmuir-Blodgett coatings and their application to sensing of SO2 and NO2 in the presence of a large excess of oxygen. Practical usefulness and future prospects of this new family of sensors in comparison with alternative systems are discussed.
引用
收藏
页码:213 / 218
页数:6
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