UTERINE AND CARDIOVASCULAR EFFECTS OF AMINOPHYLLINE

被引：17

作者：

LIPSHITZ, J

机构：

[1] GROOTE SCHUUR HOSP,CAPE TOWN,SOUTH AFRICA

[2] UNIV CAPE TOWN,DEPT OBSTET & GYNECOL,CAPE TOWN 7900,SOUTH AFRICA

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 1978年 / 131卷 / 07期

关键词：

D O I：

10.1016/0002-9378(78)90232-6

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Aminophylline (250 mg., over five minutes) was infused intravenously to 10 patients with oxytocin-induced contractions. The uterine activity decreased to 87 per cent because of the effect on contraction intensity; contraction frequency was unaffected. The maximum maternal pulse rate increased to 33 beats per minute. Blood pressure was unaffected. The fetal heart rate and beat-to-beat variability increased. An increased dosage of aminophylline produced unacceptably high maternal tachycardia. Comparing the results to those produced by the β-sympathomimetic drugs in the same experimental model, it is concluded that aminophylline exhibits poor uterine selectivity with an unfavorable cardiovascular/tocolytic ratio. © 1978.

引用

页码：716 / 718

页数：3

共 6 条

[1] INHIBITION OF UTERINE MOTILITY BY AMINOPHYLLINE [J].