AN UNUSUALLY FACILE [3,3]-SIGMATROPIC REARRANGEMENT IN A STEREOSPECIFIC SYNTHESIS OF NOVEL 2',3'-DIDEOXYNUCLEOSIDE PRECURSORS

被引：14

作者：

ARMSTRONG, PL

COULL, IC

HEWSON, AT

SLATER, MJ

机构：

[1] SHEFFIELD HALLAM UNIV, DIV CHEM, SHEFFIELD S1 1WB, S YORKSHIRE, ENGLAND

[2] SHEFFIELD HALLAM UNIV, HLTH RES INST, SHEFFIELD S1 1WB, S YORKSHIRE, ENGLAND

[3] WELLCOME RES LABS, BECKENHAM BR3 3BS, KENT, ENGLAND

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 24期

关键词：

D O I：

10.1016/0040-4039(95)00747-Z

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The glycal 5 is converted to intermediates which undergo, under mild conditions, thermal aza-Claisen rearrangements, leading to the amides 7 and 8 and the 2-pyrimidone 9, all potential precursors to 2',3'-dideoxynucleosides.

引用

页码：4311 / 4314

页数：4

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