SYNTHESIS AND KINETIC-STUDIES OF A SIMPLE PROSTACYCLIN MODEL

[1] (Z)-6,9-EPOXYNON-5-ENOIC ACID - A SIMPLE-MODEL WHICH MIMICS THE UNUSUAL HYDROLYTIC LABILITY OF PROSTACYCLIN [J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1986, (17) : 1366 - 1368

[2] BERGMAN NA, UNPUB

[3] HYDROLYSIS OF ORTHO ESTERS - FURTHER INVESTIGATION OF THE FACTORS WHICH CONTROL THE RATE-DETERMINING STEP [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1983, 105 (23) : 6852 - 6855

[4] CATALYSIS BY UNDISSOCIATED H3PO4 IN AQUEOUS H2PO4-/HPO42- BUFFER SOLUTIONS - DEPENDENCE ON THE MAGNITUDE OF THE BRONSTED EXPONENT [J]. JOURNAL OF ORGANIC CHEMISTRY, 1986, 51 (21) : 4035 - 4037

[5] PROSTACYCLIN - EVIDENCE THAT INTRAMOLECULAR GENERAL-ACID CATALYSIS BY ITS CARBOXYLIC-ACID GROUP IS RESPONSIBLE FOR THE EXTRA HYDROLYTIC LABILITY [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1986, 108 (14) : 4192 - 4196

[6] CHEMICAL STABILITY OF PROSTACYCLIN (PGI2) IN AQUEOUS-SOLUTIONS [J]. PROSTAGLANDINS, 1978, 15 (06): : 943 - 954

[7] STEREO-CONTROLLED SYNTHESIS OF PROSTAGLANDINS F2ALPHA AND E2 (DL) [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1969, 91 (20) : 5675 - +

[8] Johnson K. J., 1980, NUMERICAL METHODS CH

[9] SYNTHESIS AND CHARACTERIZATION OF PROSTACYCLIN, 6-KETOPROSTAGLANDIN F-1-ALPHA, PROSTAGLANDIN I-1, AND PROSTAGLANDIN I-3 [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1978, 100 (24) : 7690 - 7705

[10] KRESGE AJ, 1979, J CHEM SOC CHEM COMM, P129

[1] (Z)-6,9-EPOXYNON-5-ENOIC ACID - A SIMPLE-MODEL WHICH MIMICS THE UNUSUAL HYDROLYTIC LABILITY OF PROSTACYCLIN [J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1986, (17) : 1366 - 1368

[2] BERGMAN NA, UNPUB

[3] HYDROLYSIS OF ORTHO ESTERS - FURTHER INVESTIGATION OF THE FACTORS WHICH CONTROL THE RATE-DETERMINING STEP [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1983, 105 (23) : 6852 - 6855

[4] CATALYSIS BY UNDISSOCIATED H3PO4 IN AQUEOUS H2PO4-/HPO42- BUFFER SOLUTIONS - DEPENDENCE ON THE MAGNITUDE OF THE BRONSTED EXPONENT [J]. JOURNAL OF ORGANIC CHEMISTRY, 1986, 51 (21) : 4035 - 4037

[5] PROSTACYCLIN - EVIDENCE THAT INTRAMOLECULAR GENERAL-ACID CATALYSIS BY ITS CARBOXYLIC-ACID GROUP IS RESPONSIBLE FOR THE EXTRA HYDROLYTIC LABILITY [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1986, 108 (14) : 4192 - 4196

[6] CHEMICAL STABILITY OF PROSTACYCLIN (PGI2) IN AQUEOUS-SOLUTIONS [J]. PROSTAGLANDINS, 1978, 15 (06): : 943 - 954

[7] STEREO-CONTROLLED SYNTHESIS OF PROSTAGLANDINS F2ALPHA AND E2 (DL) [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1969, 91 (20) : 5675 - +

[8] Johnson K. J., 1980, NUMERICAL METHODS CH

[9] SYNTHESIS AND CHARACTERIZATION OF PROSTACYCLIN, 6-KETOPROSTAGLANDIN F-1-ALPHA, PROSTAGLANDIN I-1, AND PROSTAGLANDIN I-3 [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1978, 100 (24) : 7690 - 7705

[10] KRESGE AJ, 1979, J CHEM SOC CHEM COMM, P129