ADENOSINE TRIPHOSPHATE AND ADENOSINE TRIPHOSPHATASE IN HORMONE-CONTAINING GRANULES OF POSTERIOR PITUITARY GLAND

被引：40

作者：

POISNER, AM

DOUGLAS, WW

机构：

[1] Department of Pharmacology, Albert Einstein College of Medicine, New York, NY

来源：

SCIENCE | 1968年 / 160卷 / 3824期

关键词：

D O I：

10.1126/science.160.3824.203

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Neurosecretory granules prepared from bovine posterior pituitary glands by cell fractionation methods contain adenosine triphosphate and adenosine triphosphatase activity. Addition of adenosine triphosphate to suspensions of granules stimulates release of vasopressin. It is suggested that adenosine triphosphate and adenosine triphosphatase participate in the storage and release of vasopressin.

引用

收藏

页码：203 / &

相关论文

共 24 条

[1] OUTFLUX OF VARIOUS PHOSPHATES DURING MEMBRANE DEPOLARIZATION OF EXCITABLE TISSUES [J].

ABOOD, LG ;

MIYAMOTO, S ;

KOKETSU, K .

AMERICAN JOURNAL OF PHYSIOLOGY, 1962, 202 (03) :469-&

[2] ADENOSINE-TRIPHOSPHATASE ACTIVITY OF ADRENAL CHROMAFFIN GRANULES [J].

BANKS, P .

BIOCHEMICAL JOURNAL, 1965, 95 (02) :490-&

[3] OBSERVATIONS ON THE DISTRIBUTION OF CATECHOL AMINES AND ADENOSINETRIPHOSPHATE IN THE BOVINE ADRENAL MEDULLA [J].

BLASCHKO, H ;

BORN, GVR ;

DIORIO, A ;

EADE, NR .

JOURNAL OF PHYSIOLOGY-LONDON, 1956, 133 (03) :548-557

[4]

BORN GVR, 1957, J PHYSIOL-LONDON, V137, pP82

[5]

CORI CF, 1963, PERSPECTIVES BIOL ED, P75

[6] ISOLATION OF PURIFIED NEUROSECRETORY GRANULES FROM BOVINE PITUITARY POSTERIOR LOBES - COMPARISON OF GRANULE PROTEIN CONSTITUENTS WITH THOSE OF NEUROPHYSIN [J].

DEAN, CR ;

HOPE, DB .

BIOCHEMICAL JOURNAL, 1967, 104 (03) :1082-+

[7] EVIDENCE THAT SECRETING ADRENAL CHROMAFFIN CELL RELEASES CATECHOLAMINES DIRECTLY FROM ATP-RICH GRANULES [J].

DOUGLAS, WW ;

POISNER, AM .

JOURNAL OF PHYSIOLOGY-LONDON, 1966, 183 (01) :236-+

[8]

DOUGLASS WW, 1964, J PHYSIOL-LONDON, V172, P1

[9]

Du Vigneaud V, 1958, J AM CHEM SOC, V80, P3355

[10] CONTENT AND INTRACELLULAR DISTRIBUTION OF ADENOSINE TRIPHOSPHATE IN COW ADRENAL MEDULLA [J].

FALCK, B ;

HILLARP, NA ;

HOGBERG, B .

ACTA PHYSIOLOGICA SCANDINAVICA, 1956, 36 (04) :360-376