ANALYSIS OF PHENYLETHYLAMINES BY GAS-CHROMATOGRAPHY - CHEMICAL IONIZATION MASS-SPECTROMETRY

被引:15
作者
EDWARDS, DJ
DOSHI, PS
HANIN, I
机构
[1] Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh
关键词
D O I
10.1016/0003-2697(79)90586-4
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A method is described for the simultaneous analysis of several biologically important phenylethylamines using gas chromatography/mass spectrometry. The amines are converted to N-dinitrophenyl, O-trimethylsilyl derivatives prior to their separation by gas chromatography. By using selected ion monitoring in the chemical ionization mode, we have been able to quantitate the endogenous concentrations of phenylethylamine and phenylethanolamine in rat brain. © 1979.
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页码:308 / 316
页数:9
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