NUCLEOTIDE-SEQUENCE OF A ASPERGILLUS-PARASITICUS GENE STRONGLY REPRESSED BY THIAMINE

被引：16

作者：

CARY, JW

BHATNAGAR, D

机构：

[1] USDA-ARS-Southern Regional Research Center, New Orleans, LA 70179

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1995年 / 1261卷 / 02期

关键词：

GENE REGULATION; NUCLEOTIDE SEQUENCE; THIAMINE; AFLATOXIN; (ASPERGILLUS);

D O I：

10.1016/0167-4781(95)00032-C

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A cDNA clone demonstrating a high degree of homology to the thiamine repressed nmt1 gene of Schizosaccharomyces pombe was isolated from the aflatoxigenic fungus; Aspergillus parasiticus. The deduced polypeptide of a cDNA clone from A. parasiticus had an amino acid sequence identity of 60% with that of the nmtI gene of S. pombe. Transcription of the nmt1 gene homolog in the fungus was strongly inhibited by concentrations of thiamine of 2.0 mu M or higher.

引用

页码：319 / 320

页数：2

共 7 条

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