NEW C-2 SYMMETRICAL BIS-AZIRIDINES - EFFICIENT SYNTHESIS OF (2S,5S)-1,6-DI(P-TOLUENESULFONYLOXY)-2,5-HEXENEDIOL AND (2S,3E,5S)-1,6-DI(P-TOLUENESULFONYLOXY)-2,5-HEXENEDIOL

被引：14

作者：

FITREMANN, J ^{[1
]}

DUREAULT, A ^{[1
]}

DEPEZAY, JC ^{[1
]}

机构：

[1] UNIV PARIS 05,CNRS,CHIM & BIOCHIM PHARMACOL & TOXICOL LAB,F-75270 PARIS 06,FRANCE

来源：

TETRAHEDRON | 1995年 / 51卷 / 35期

关键词：

D O I：

10.1016/0040-4020(95)00533-E

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The regioselective tosylation and functionalization of (S,S)-1,2,5,6-hexanetetrol is reported. The reductive aminocyclization of conformationally flexible diazidodiols by PPh(3) leads to C-2 symmetric bis-aziridines and to substituted furans.

引用

页码：9581 / 9594

页数：14

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