HYPOXIA AND PULMONARY ARTERIAL PRESSURE IN RABBIT

被引：20

作者：

OWENTHOMAS, JB

REEVES, JT

机构：

来源：

JOURNAL OF PHYSIOLOGY-LONDON | 1969年 / 201卷 / 03期

关键词：

D O I：

10.1113/jphysiol.1969.sp008779

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

1. The effect of hypoxia on pulmonary arterial pressure was studied in young and adult rabbits. 2. In isolated perfused lungs, hypoxia caused no rise in pulmonary arterial pressure in rabbits on the day of birth. The size of the hypoxic response increased progressively until 9–11 days of age, when the adult response of a 20% rise of pulmonary arterial pressure at constant flow was attained. 3. The intact adult rabbit responded to hypoxia with a 14–30% rise in pulmonary arterial pressure, attributed to vasoconstriction and independent of frequency or tidal volume during positive pressure ventilation. © 1969 The Physiological Society

引用

页码：665 / +

页数：1

共 19 条

[1] DIRECT TENSION RECORDING FROM SMOOTH MUSCLE OF RESISTANCE VESSELS FROM VARIOUS ORGANS [J].

BOHR, DF ;

TAQUINI, AC ;

GOULET, PL .

ANGIOLOGY, 1961, 12 (10) :478-&

[2] CONDITIONS GOVERNING PULMONARY VASCULAR RESPONSE TO VENTILATION HYPOXIA AND HYPOXAEMIA IN DOG [J].

DALY, IDB ;

MICHEL, CC ;

RAMSAY, DJ ;

WAALER, BA .

JOURNAL OF PHYSIOLOGY-LONDON, 1968, 196 (02) :351-+

[3] PRESSURE MEASUREMENTS IN LESSER CIRCULATION OF NEWBORN RABBIT [J].

DENNIS, J .

QUARTERLY JOURNAL OF EXPERIMENTAL PHYSIOLOGY AND COGNATE MEDICAL SCIENCES, 1968, 53 (02) :136-&

[4] AGENTS ACTING ON THE LUNG CIRCULATION [J].

DIRKEN, MNJ ;

HEEMSTRA, H .

QUARTERLY JOURNAL OF EXPERIMENTAL PHYSIOLOGY AND COGNATE MEDICAL SCIENCES, 1948, 34 (03) :227-241

[5] THE ADAPTATION OF THE LUNG CIRCULATION TO THE VENTILATION [J].

DIRKEN, MNJ ;

HEEMSTRA, H .

QUARTERLY JOURNAL OF EXPERIMENTAL PHYSIOLOGY AND COGNATE MEDICAL SCIENCES, 1948, 34 (03) :213-226

[6] ALVEOLAR OXYGEN TENSION AND LUNG CIRCULATION [J].

DIRKEN, MNJ ;

HEEMSTRA, H .

QUARTERLY JOURNAL OF EXPERIMENTAL PHYSIOLOGY AND COGNATE MEDICAL SCIENCES, 1948, 34 (03) :193-211

[7] PULMONARY VASOMOTOR RESPONSES OF ISOLATED PERFUSED CAT LUNGS TO ANOXIA [J].

DUKE, HN ;

KILLICK, EM .

JOURNAL OF PHYSIOLOGY-LONDON, 1952, 117 (03) :303-316

[8]

DUKE HN, 1968, LANCET, V2, P21

[9]

Gilbert AJ, 1938, J PHARMACOL EXP THER, V62, P228

[10] VASOCONSTRICTION IN ISOLATED BLOOD-PERFUSED RABBIT LUNGS AND ITS INHIBITION BY CRESOLS [J].

HAUGE, A ;

LUNDE, PKM ;

WAALER, BA .

ACTA PHYSIOLOGICA SCANDINAVICA, 1966, 66 (1-2) :226-&

← 1 2 →