STEREOCHEMICAL STUDIES IN SUBSTITUTED CYCLOPENTANECARBOXYLATES

Assignment of stereochemistry is made to the pairs of esters 3-4 and 13-14, prepared from the hydrogenation of 1 and 2, respectively. The stereochemical course of the reaction of cyclohexane and acetyl chloride to give 2-methylacetylcyclopentane and of the alkylation of ketone 18 was reinvestigated. Compounds 3-20 exhibit a systematic variation in their nmr spectra, characteristic of each geometric series. © 1969, American Chemical Society. All rights reserved.