ISOLATION AND CHARACTERIZATION OF IRRADIATION FUSION HYBRIDS FROM MOUSE CHROMOSOME-1 FOR MAPPING RMC-1, A GENE ENCODING A CELLULAR RECEPTOR FOR MCF CLASS MURINE RETROVIRUSES

被引：18

作者：

HUNTER, K ^{[1
]}

HOUSMAN, D ^{[1
]}

HOPKINS, N ^{[1
]}

机构：

[1] MIT,CTR CANC RES,CAMBRIDGE,MA 02139

来源：

SOMATIC CELL AND MOLECULAR GENETICS | 1991年 / 17卷 / 02期

关键词：

D O I：

10.1007/BF01232974

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An irradiation-reduced somatic cell hybrid mapping panel was constructed of BALB/c mouse Chromosome 1. Nineteen hybrids were selected from a pool of 292 clones to generate a fine structure physical map of the distal 40 cM of the chromosome. The hybrids contain mouse DNA fragments only from Chromosome 1, ranging from approximately 5 cM to approximately 20 cM. Utilizing a viral infectibility assay, a cellular receptor gene, Rmc-1, for the MCF class of murine retroviruses was found to be linked to Lamb2, in the region between the Lamb2 and Bxv-1 loci. In addition, analysis of the hybrid mapping panel resulted in the remapping of three loci, Atpb, Ly-5, and Pmv-24, as compared to the mouse linkage map. Two previously unmapped endogenous proviruses are also putatively assigned positions on the chromosome.

引用

收藏

页码：169 / 183

页数：15

相关论文

共 54 条

[1]

ALBRITTON LM, 1989, CELL, V57, P658

[2] SERIAL TRANSFER OF A HUMAN GENE TO RODENT CELLS BY SEQUENTIAL CHROMOSOME-MEDIATED GENE TRANSFER [J].

ATHWAL, RS ;

MCBRIDGE, OW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (07) :2943-2947

[3] VIRAL RNA-DEPENDENT DNA POLYMERASE - RNA-DEPENDENT DNA POLYMERASE IN VIRIONS OF RNA TUMOUR VIRUSES [J].

BALTIMORE, D .

NATURE, 1970, 226 (5252) :1209-+

[4] SEQUENCING OF LAMININ-B CHAIN CDNAS REVEALS C-TERMINAL REGIONS OF COILED-COIL ALPHA-HELIX [J].

BARLOW, DP ;

GREEN, NM ;

KURKINEN, M ;

HOGAN, BLM .

EMBO JOURNAL, 1984, 3 (10) :2355-2362

[5] ANALYSIS OF THE ENV GENE OF A MOLECULARLY CLONED AND BIOLOGICALLY-ACTIVE MOLONEY MINK CELL FOCUS-FORMING PROVIRAL DNA [J].

BOSSELMAN, RA ;

VANSTRAATEN, F ;

VANBEVEREN, C ;

VERMA, IM ;

VOGT, M .

JOURNAL OF VIROLOGY, 1982, 44 (01) :19-31

[6] GAMMA-CRYSTALLIN FAMILY OF THE MOUSE LENS - STRUCTURAL AND EVOLUTIONARY RELATIONSHIPS [J].

BREITMAN, ML ;

LOK, S ;

WISTOW, G ;

PIATIGORSKY, J ;

TRETON, JA ;

GOLD, RJM ;

TSUI, LC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (24) :7762-7766

[7] CONSTRUCTION AND APPLICATIONS OF A HIGHLY TRANSMISSIBLE MURINE RETROVIRUS SHUTTLE VECTOR [J].

CEPKO, CL ;

ROBERTS, BE ;

MULLIGAN, RC .

CELL, 1984, 37 (03) :1053-1062

[8] INTRACISTERNAL A-PARTICLE GENES - STRUCTURE OF ADJACENT GENES AND MAPPING OF THE BOUNDARIES OF THE TRANSCRIPTIONAL UNIT [J].

COLE, MD ;

ONO, M ;

HUANG, RCC .

JOURNAL OF VIROLOGY, 1982, 42 (01) :123-130

[9] RADIATION HYBRID MAPPING - A SOMATIC-CELL GENETIC METHOD FOR CONSTRUCTING HIGH-RESOLUTION MAPS OF MAMMALIAN CHROMOSOMES [J].

COX, DR ;

BURMEISTER, M ;

PRICE, ER ;

KIM, S ;

MYERS, RM .

SCIENCE, 1990, 250 (4978) :245-250

[10] THE CD4 (T4) ANTIGEN IS AN ESSENTIAL COMPONENT OF THE RECEPTOR FOR THE AIDS RETROVIRUS [J].

DALGLEISH, AG ;

BEVERLEY, PCL ;

CLAPHAM, PR ;

CRAWFORD, DH ;

GREAVES, MF ;

WEISS, RA .

NATURE, 1984, 312 (5996) :763-767

← 1 2 3 4 5 6 →